[PHNUTR-L] Relationship between fasting serum glucose, age,
BMI and serum 25 hydroxyvitamin D in postmenopausal women
Kathrynne Holden, MS, RD
fivestar at nutritionucanlivewith.com
Tue Jun 21 10:34:11 PDT 2005
Colleagues, the following is FYI and does not necessarily reflect my own
opinion. I have no further knowledge of the topic.
Clin Endocrinol (Oxf). 2005 Jun;62(6):738-41.
Relationship between fasting serum glucose, age, body mass index
and serum 25 hydroxyvitamin D in postmenopausal women.
Need AG, O'loughlin PD, Horowitz M, Nordin BE.
Division of Clinical Biochemistry, Institute of Medical and
Veterinary Science, University of Adelaide, Adelaide, SA, Australia.
Objective Because it has been reported that vitamin D, given to mother
or infant, can prevent type I diabetes in children, that diabetes is
more common in adults with low serum vitamin D and that insulin
secretion and action are related to vitamin D levels in healthy young
adults we examined the relationship between serum vitamin D metabolites
and fasting serum glucose in patients attending our outpatient clinics.
Retrospective examination of convenience sample of postmenopausal women
attending our osteoporosis clinics.
A total of 753 postmenopausal women attending a university hospital
outpatient clinic and not on any treatment known to affect glucose
Body weight and height, serum 25-hydroxyvitamin D [25(OH)D], serum
1,25-dihydroxyvitamin D [1,25(OH)(2)D], serum PTH and fasting serum
On simple correlation fasting serum glucose was a positive function of
age (P < 0.05), weight (P < 0.001) and body mass index (BMI) (P < 0.001)
and a negative function of serum 25(OH)D (P < 0.001), but it was not
significantly related to either serum 1,25(OH)(2)D, PTH or creatinine.
When fasting serum glucose was regressed simultaneously on age, BMI and
25(OH)D, glucose was still an inverse function of 25(OH)D (P = 0.006).
Fasting serum glucose increased as 25(OH)D levels fell throughout the
range of serum 25(OH)D measured but the greatest increase was observed
in those with 25(OH)D below 40 nmol/l.
PMID: 15943837 [PubMed - in process]
Kathrynne Holden, MS, RD < fivestar at nutritionucanlivewith.com >
"Ask the Parkinson Dietitian" http://www.parkinson.org/
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