[PHNUTR-L] Exercise and diet can reduce neuropathic pain and help
regenerate nerve fibers in impaired glucose tolerance
Kathrynne Holden, MS, RD
fivestar at nutritionucanlivewith.com
Thu Apr 6 17:32:15 PDT 2006
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Source: American Academy of Neurology (AAN)
Released: Fri 24-Mar-2006, 12:00 ET
Embargo expired: Wed 05-Apr-2006, 17:15 ET
Exercise and Diet Program Improves Damaged Nerves and Reduces Pain
Exercise and diet can reduce neuropathic pain and help regenerate nerve
fibers in patients with impaired glucose tolerance ("Prediabetes").
Newswise — Exercise and diet can reduce neuropathic pain and help
regenerate nerve fibers in patients with impaired glucose tolerance
("Prediabetes"), according to research that will be presented at the
American Academy of Neurology 58th Annual Meeting in San Diego, Calif.,
April 1 – 8, 2006.
Impaired glucose tolerance is found in 40 percent of patients with
idiopathic neuropathy (nerve damage with no identified secondary cause).
Impaired glucose tolerance neuropathy (IGTN) is characterized by loss of
nerve fibers in the skin, and is painful. It is thought that IGTN
represents the earliest stage of diabetic neuropathy. Prior research
indicates diabetic neuropathy does not improve with currently available
treatment. Patients with impaired glucose tolerance are at risk for
developing diabetes, a risk which can be reduced with a program of diet
and exercise counseling. To test whether this same program could improve
IGTN, a research team led by Dr. A. Gordon Smith and Dr. Rob Singleton
studied 32 patients over the course of one year while they received
individualized dietary and exercise counseling.
They found that the number of nerve fibers (measured by taking a small
skin biopsy) improved by approximately one third, although patients with
the worst loss of nerve fibers in their extremities did not improve.
Overall, patients had reduced pain and better functioning of their
“These findings indicate diet and exercise counseling for patients with
impaired glucose tolerance neuropathy may result in nerve regeneration,”
said the study’s lead author A. Gordon Smith, MD, of the University of
Utah. "This finding is significant because it suggests the earliest
stage of prediabetic nerve injury may be reversible."
This study was supported by the National Institutes of Health.
The American Academy of Neurology, an association of more than 19,000
neurologists and neuroscience professionals, is dedicated to improving
patient care through education and research. A neurologist is a doctor
with specialized training in diagnosing, treating and managing disorders
of the brain and nervous system such as Alzheimer disease, epilepsy,
multiple sclerosis, Parkinson disease, and stroke.
For more information about the American Academy of Neurology, visit
Editor’s Note: Dr. Smith will present this research during a scientific
platform session at 2:15 p.m. on Wednesday, April 5 in room 2 of the San
Diego Convention Center.
Kathrynne Holden, MS, RD < fivestar at nutritionucanlivewith.com >
"Ask the Parkinson Dietitian" http://www.parkinson.org/
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