[PHNUTR-L] Curry colouring and fat mix could help diabetics
Kathrynne Holden, MS, RD
fivestar at nutritionucanlivewith.com
Thu Apr 13 05:55:52 PDT 2006
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Public release date: 12-Apr-2006
Contact: Miguel Holland
Curry colouring and fat mix could help diabetics
Brisbane immunologist Dr Brendan O'Sullivan hopes to put a dent in
skyrocketing rates of diabetes in Australia by creating a new treatment
for Type 2 diabetes.
The Senior Research Officer and his team at UQ's Centre for Immunology
and Cancer Research (CICR) are developing a drug that targets liver
cells to prevent their inflammation in obesity -- a common precursor to
Dr O'Sullivan has received a three-year $150,000 Smart State Fellowship
from the State Government to explore potential diabetes treatments.
Arthritis Queensland and the CICR will also contribute a further
$150,000 each during the project.
People with Type 2 diabetes cannot produce enough insulin or do not use
the insulin they produce properly.
Insulin is a hormone produced by the pancreas which moves sugar from the
food we eat into the body's cells.
Dr O'Sullivan said his technique involved coating treatment drugs in
absorbable fat which formed an injectable dose that could last up to one
"One of the drugs we're using is curcumin, which is basically the yellow
compound that you see in curries, which is an anti-inflammatory
compound," Dr O'Sullivan said.
"The idea is to encapsulate that compound and then deliver it to the
liver cells to prevent them from producing all these inflammatory
Early results show his method works in mice but he said his grant would
validate the best method to use in human trials.
The 36-year-old from Kedron said that, if successful, the treatment
could combat other diseases such as heart disease, osteoarthritis,
rheumatoid arthritis and lupus, an autoimmune disease against the skin.
His Fellowship will pay for staff, lab and research work.
UQ's Deputy Vice-Chancellor (Research) Professor David Siddle said Dr
O'Sullivan's project was one of many leading-edge CICR projects.
"Our determined immunologists are tackling some of society's worst
diseases with great science," Professor Siddle said.
Kathrynne Holden, MS, RD < fivestar at nutritionucanlivewith.com >
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