[PHNUTR-L] Bone mineral density in children with celiac disease.
Effect of a Gluten-free diet
Kathrynne Holden, MS, RD
fivestar at nutritionucanlivewith.com
Mon Apr 17 07:08:44 PDT 2006
Colleagues, the following is FYI and does not necessarily reflect my own
opinion. I have no further knowledge of the topic. If you do not wish to
receive these posts, set your email filter to filter out any messages
coming from @nutritionucanlivewith.com and the program will remove
anything coming from me.
Positive Effect of a Gluten-Free Diet on Bone Mineral Density in
Children with Celiac Disease
Reference: “Bone mineral density in children with celiac disease.
Effect of a Gluten-free diet,” Tau C, Mautalen C, et al, Eur J Clin
Nutr., 2006; 60(3): 358-63. (Address: Metabolismo Calcico y Oseo,
Endocrinologia, Hospital de Pediatria J.P. Garrahan, Buenos Aires,
Argentina. E-Mail: cristinatau at uol.com.ar ).
Summary: In a longitudinal and prospective study involving 24 children
diagnosed with celiac disease (18 girls, 6 boys; 16 under the age of 4
years and 8 over the age of 4 years), 58% of the children were found to
have low (below -1 standard deviation) axial bone mineral density (BMD),
which reverted to normal in most children under the age of 4 years who
strictly adhered to a gluten-free diet. At baseline, mean BMD was 0.46
g/cm(2), the BMD Z-score was -1.36 and was below -1 standard deviation
in 14 children (58%). After 1.17 years on a gluten-free diet, mean BMD
increased to 0.55 g/cm(2), and BMD Z-score improved to -0.23. Adherence
to the gluten-free diet led to a significant increase in bone mineral
content (BMC) and BMD in all children. However, BMD increased by more
than 1 standard deviation in 15 of the 16 children under the age of 4
years and in only 4 of the 8 children over the age of 4 years, some of
whom did not strictly follow the gluten-free diet. Additionally, heigh t
and weight significantly increased with the gluten-free diet, and this
increase was found to be positively correlated with the increase in BMD.
Thus, these findings suggest that a gluten-free diet significantly
increases BMD in children with celiac disease having low BMD, especially
those under the age of 4 years.
Kathrynne Holden, MS, RD < fivestar at nutritionucanlivewith.com >
"Ask the Parkinson Dietitian" http://www.parkinson.org/
"Eat well, stay well with Parkinson's disease"
"Parkinson's disease: Guidelines for Medical Nutrition Therapy"
More information about the PHNUTR-L