[PHNUTR-L] Re: [DCE] Re: Daily diet of grapefruit minimizes risk
factor for heart disease
Kathrynne Holden, MS, RD
fivestar at nutritionucanlivewith.com
Sun Feb 19 09:57:43 PST 2006
Raphaela Rozanski wrote:
> This is interesting. What about the medication interaction for the various treatments for lowering cholesterol? Raphaela
The last paragraph has a brief acknowledgment of the interaction.
>>From: "Kathrynne Holden, MS, RD" <fivestar at nutritionucanlivewith.com>
>>Date: Thu Feb 16 08:14:52 CST 2006
>>To: Dietetics-L <dietetics-l at list.eatright.org>
>>Cc: Public Health Nutrition List <phnutr-l at u.washington.edu>,
> Food and Nutrition Specialists <fnspec at purdue.edu>,
> Diabetes Care and Education DPG <dce at v2.listbox.com>
>>Subject: Daily diet of grapefruit minimizes risk factor for heart disease
>>Colleagues, the following is FYI and does not necessarily reflect my own
>>opinion. I have no further knowledge of the topic. If you do not wish to
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>>Public release date: 15-Feb-2006
>>Contact: Jerry Barach
>>jerryb at savion.huji.ac.il
>>The Hebrew University of Jerusalem
>>Daily diet of grapefruit minimizes risk factor for heart disease
>>Dr. Shela Gorinstein at a citrus fruit stand in the Mahane Yehuda
>>outdoor market in Jerusalem. Photo by Sasson Tiram
>>Heart disease patients who eat one grapefruit daily can significantly
>>reduce the levels of cholesterol in their blood in comparison to
>>patients who do not eat the fruit, a new study has found. Chronic high
>>blood cholesterol is a major risk factor for heart disease.
>>The study was conducted by a group of scientists under the leadership of
>>Dr. Shela Gorinstein of the Hebrew University School of Pharmacy,
>>Department of Medicinal Chemistry and Natural Products, in cooperation
>>with Prof. Abraham Caspi, head of the Institute of Cardiology at Kaplan
>>Hospital in Rehovot. In addition, scientists from Poland and Singapore
>>participated in laboratory work connected with the project.
>>The study, which strengthens a growing body of evidence supporting the
>>heart benefits of eating citrus fruit, was published this month on the
>>website of the American Chemical Society's Journal of Agricultural and
>>Food Chemistry. The study will appear in the journal's March 22 print issue.
>>February has been designated in the U.S. as American Heart Month. In the
>>U.S., heart disease is the number one killer of women.
>>The grapefruit study included 57 patients at Kaplan Hospital, both men
>>and women, with hyperlipidemia (high blood cholesterol) who recently had
>>coronary bypass surgery and did not take statin drugs during the study
>>period. Statins are commonly prescribed to lower cholesterol.
>>The patients, equally divided into three treatment groups, were given
>>either a single serving of fresh red grapefruit, white (blond)
>>grapefruit or no grapefruit, along with regular, balanced meals for 30
>>consecutive days. Israeli Jaffa red Star Ruby and white grapefruit
>>varieties were used in this study.
>>The patients who received either red or white grapefruit showed
>>significant decreases in blood lipid levels, whereas the patients that
>>did not eat grapefruit showed no changes in lipid levels, according to
>>the researchers. Red grapefruit was more effective than white in
>>lowering lipids, particularly blood triglycerides, a type of cholesterol
>>whose elevated levels are often associated with heart problems, the
>>Grapefruit has an antioxidant action that provides a beneficial health
>>benefit, says Dr. Gorinstein, adding that the red variety generally has
>>a higher level of antioxidants than the white. But it's also possible
>>that red grapefruit may contain currently unknown chemicals that are
>>responsible for the observed triglyceride-lowering effect, she says.
>>Additional studies are planned.
>>Both the fresh fruit and the juice are believed to be equally
>>beneficial, Dr. Gorinstein and her associates say. One cup of fresh
>>grapefruit is roughly equivalent to half a cup of juice.
>>Grapefruit is known to interact with certain medications --sometimes
>>adversely -- so the researchers caution people on prescription
>>medication to consult with their doctor or pharmacist to determine
>>whether their medicine will interact before consuming grapefruit products.
>>Kathrynne Holden, MS, RD < fivestar at nutritionucanlivewith.com >
>>"Ask the Parkinson Dietitian" http://www.parkinson.org/
>>"Eat well, stay well with Parkinson's disease"
>>"Parkinson's disease: Guidelines for Medical Nutrition Therapy"
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