[PHNUTR-L] Re: [DCE] Re: Daily diet of grapefruit minimizes risk factor for heart disease

[Kathrynne Holden, MS, RD]

Raphaela Rozanski wrote:


> This is interesting. What about the medication interaction for the various treatments for lowering cholesterol? Raphaela 


The last paragraph has a brief acknowledgment of the interaction.
- Kathrynne


>>From: "Kathrynne Holden, MS, RD" <fivestar at nutritionucanlivewith.com>

>>Date: Thu Feb 16 08:14:52 CST 2006

>>To: Dietetics-L <dietetics-l at list.eatright.org>

>>Cc: Public Health Nutrition List <phnutr-l at u.washington.edu>, 

> 

> 	Food and Nutrition Specialists <fnspec at purdue.edu>, 

> 	Diabetes Care and Education DPG <dce at v2.listbox.com>

> 

>>Subject: Daily diet of grapefruit minimizes risk factor for heart disease

> 

> 

>>Colleagues, the following is FYI and does not necessarily reflect my own

>>opinion. I have no further knowledge of the topic. If you do not wish to

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>>---------------------------------------------------------

>>Public release date: 15-Feb-2006

>>http://www.eurekalert.org/pub_releases/2006-02/thuo-ddo021506.php

>>

>>Contact: Jerry Barach

>>jerryb at savion.huji.ac.il

>>97-22-588-2904

>>The Hebrew University of Jerusalem

>>

>>Daily diet of grapefruit minimizes risk factor for heart disease

>>

>>Dr. Shela Gorinstein at a citrus fruit stand in the Mahane Yehuda 

>>outdoor market in Jerusalem. Photo by Sasson Tiram

>>

>>Heart disease patients who eat one grapefruit daily can significantly 

>>reduce the levels of cholesterol in their blood in comparison to 

>>patients who do not eat the fruit, a new study has found. Chronic high 

>>blood cholesterol is a major risk factor for heart disease.

>>

>>The study was conducted by a group of scientists under the leadership of 

>>Dr. Shela Gorinstein of the Hebrew University School of Pharmacy, 

>>Department of Medicinal Chemistry and Natural Products, in cooperation 

>>with Prof. Abraham Caspi, head of the Institute of Cardiology at Kaplan 

>>Hospital in Rehovot. In addition, scientists from Poland and Singapore 

>>participated in laboratory work connected with the project.

>>

>>The study, which strengthens a growing body of evidence supporting the 

>>heart benefits of eating citrus fruit, was published this month on the 

>>website of the American Chemical Society's Journal of Agricultural and 

>>Food Chemistry. The study will appear in the journal's March 22 print issue.

>>

>>February has been designated in the U.S. as American Heart Month. In the 

>>U.S., heart disease is the number one killer of women.

>>

>>The grapefruit study included 57 patients at Kaplan Hospital, both men 

>>and women, with hyperlipidemia (high blood cholesterol) who recently had 

>>coronary bypass surgery and did not take statin drugs during the study 

>>period. Statins are commonly prescribed to lower cholesterol.

>>

>>The patients, equally divided into three treatment groups, were given 

>>either a single serving of fresh red grapefruit, white (blond) 

>>grapefruit or no grapefruit, along with regular, balanced meals for 30 

>>consecutive days. Israeli Jaffa red Star Ruby and white grapefruit 

>>varieties were used in this study.

>>

>>The patients who received either red or white grapefruit showed 

>>significant decreases in blood lipid levels, whereas the patients that 

>>did not eat grapefruit showed no changes in lipid levels, according to 

>>the researchers. Red grapefruit was more effective than white in 

>>lowering lipids, particularly blood triglycerides, a type of cholesterol 

>>whose elevated levels are often associated with heart problems, the 

>>researchers say.

>>

>>Grapefruit has an antioxidant action that provides a beneficial health 

>>benefit, says Dr. Gorinstein, adding that the red variety generally has 

>>a higher level of antioxidants than the white. But it's also possible 

>>that red grapefruit may contain currently unknown chemicals that are 

>>responsible for the observed triglyceride-lowering effect, she says. 

>>Additional studies are planned.

>>

>>Both the fresh fruit and the juice are believed to be equally 

>>beneficial, Dr. Gorinstein and her associates say. One cup of fresh 

>>grapefruit is roughly equivalent to half a cup of juice.

>>

>>Grapefruit is known to interact with certain medications --sometimes 

>>adversely -- so the researchers caution people on prescription 

>>medication to consult with their doctor or pharmacist to determine 

>>whether their medicine will interact before consuming grapefruit products.

>>-- 

>>Kathrynne Holden, MS, RD < fivestar at nutritionucanlivewith.com >

>>"Ask the Parkinson Dietitian"  http://www.parkinson.org/

>>"Eat well, stay well with Parkinson's disease"

>>"Parkinson's disease: Guidelines for Medical Nutrition Therapy"

>>http://www.nutritionucanlivewith.com/

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