[PHNUTR-L] Concern over 'aggressive' cholesterol recommendations
Kathrynne Holden, MS, RD
fivestar at nutritionucanlivewith.com
Fri Jun 2 12:29:00 PDT 2006
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Public release date: 1-Jun-2006
Contact: Emma Dickinson
edickinson at bmj.com
BMJ-British Medical Journal
Concern over 'aggressive' cholesterol recommendations
Should we lower cholesterol as much as possible?; BMJ Volume 332, pp 1330-2
New US recommendations for lowering cholesterol levels would increase
the risk of harmful side effects with no overall reduction in deaths,
warn experts in this week's BMJ.
The American National Cholesterol Education Program has said that people
at high risk of heart disease should be treated more aggressively.
By aggressively, it means that LDL-cholesterol concentrations should be
lowered to less than 1.81 millimoles per litre of blood (mmol/l) in
high-risk individuals. Current guidelines generally recommend 2.56
mmol/l as a healthy reading.
To achieve this new goal, most of the Western world's adult population
would be on statins, and doses would have to be more than eight times
higher than currently used, say the authors. This would increase both
the number and seriousness of side effects.
But clinical trials suggest that higher doses of statins do not lower
overall mortality and side effects are generally under-reported.
The authors conclude that any reduction in non-fatal events may be
outweighed by more numerous and more severe adverse effects.
Kathrynne Holden, MS, RD < fivestar at nutritionucanlivewith.com >
"Ask the Parkinson Dietitian" http://www.parkinson.org/
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