[PHNUTR-L] Oligofructose, a Fermentable Dietary Fiber, Promotes Satiety in Healthy Adults

[Kathrynne Holden, MS, RD]

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	Oligofructose, a Fermentable Dietary Fiber, Promotes Satiety in Healthy 
Adults

Reference: 	“Oligofructose promotes satiety in healthy human: a pilot 
study,” Cani PD, Joly E, et al, Eur J Clin Nutr., 2006; 60(5): 567-72. 
(Address: Unit of Pharmacokinetics, Metabolism, Nutrition and 
Toxicology, Department of Pharmaceutical Sciences, Universite catholique 
de Louvain, Brussels, Belgium).

Summary: 	In a placebo-controlled, single-blind, crossover, pilot study 
involving 5 men and 5 women, (aged 21-39 years old; BMI 18.5 - 27.4 
kg/m(2)) dietary supplementation with oligofructose (OFS: a fermentable 
dietary fiber) was found to increase satiety following breakfast and 
dinner, and reduce hunger and prospective food consumption following 
dinner. The subjects were randomized to receive 8 g of OFS or placebo 
(dextrine maltose (DM)) twice a day (total of 16 g per day) for 2 weeks. 
After a 2-week washout period, the subjects crossed over interventions 
for another 2 weeks. Energy intake, hunger, satiety, fullness, and 
prospective food consumption were assessed with analogue scales at the 
end of each intervention period. During breakfast, OFS supplementation 
was found to significantly increase satiety, compared to DM 
supplementation. At dinner, OFS intake significantly increased satiety, 
and reduced hunger and prospective food consumption, compared to DM 
intake. Additionally, energy intake at breakfast and lunch was 
significantly lower after OFS intake, compared to DM intake. Total daily 
energy intake was 5% lower during OFS intake than during DM intake. 
Thus, this pilot study suggests that supplementation with OFS increases 
satiety in healthy adults, and therefore may play a beneficial role in 
food intake management in overweight individuals.
-- 
Kathrynne Holden, MS, RD < fivestar at nutritionucanlivewith.com >
"Ask the Parkinson Dietitian"  http://www.parkinson.org/
"Eat well, stay well with Parkinson's disease"
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