[PHNUTR-L] Average American Has "Substantial" Lifetime Risk of
Kathrynne Holden, MS, RD
fivestar at nutritionucanlivewith.com
Tue Jun 20 10:26:13 PDT 2006
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Average American Has "Substantial" Lifetime Risk of Developing Diabetes
By Martha Kerr
WASHINGTON, DC (Reuters Health) Jun 15 - Body mass index (BMI) is
tightly linked to lifetime risk of diabetes mellitus, researchers
reported at the Scientific Sessions of the American Diabetes
Association. "On average, every American has a very high risk of
diabetes," CDC investigators announced.
Using the National Health and Nutrition Examination Survey (NHANES)
data, Dr. K. M. Venkat Narayan and associates at the Centers for Disease
Control and Prevention in Atlanta, GA, calculated lifetime risk of
diabetes according to BMI for subjects aged 18 to 84.
For a normal-weight 18-year-old man, the average lifetime risk of
diabetes is 19.8%. Risk increases to 29.7% for overweight men, 57.0% for
obese men and 70.3% for very obese men.
For normal-weight women at 18 years of age, lifetime risk is 17.1%; for
overweight women it is 35.4%, for obese women it is 54.6% and for very
obese women it is 74.4%.
Those figures mean that, compared with normal weight men at age 18, the
increased lifetime risk of diabetes for overweight men is 9.9%, for
obese men, 37.2%, and for very obese men, 57.3%. Corresponding figures
for women are 18.3%, 37.5%, and 57.3%.
Men 65 years and older have a much lower lifetime risk of diabetes with
increasing BMI. Compared with normal-weight men at this age, overweight
men have a 3.7% higher risk, for obese men risk is 18.8% higher, and for
the very obese it is increased 23.9%. For older women the increased risk
is slightly higher than for older men in each weight category, but still
much lower than for younger women.
"Clearly, intervening to reduce obesity as early in life as possible is
our best tool to reduce the risk of diabetes," Dr. Narayan told meeting
CDC co-investigator Dr. Desmond E. Williams presented NHANES data from
1999-2002 on 3,030 individuals without diabetes at baseline. The purpose
of the study was to investigate an association between pre-diabetes,
defined as an impaired fasting blood glucose (IFG) of 100-125 mg/dL, and
Patients with IFG comprised 27.9% of a subset of 954 subject. They were
older, with a mean age of 49.1 compared with 40.9 years for those with
normal glucose levels, and were less likely to be women (38% vs 56%).
Of modifiable cardiovascular risk factors, the prevalence of high blood
pressure was 48.3% in those with IFG compared with 31% of those with
normal levels, enlarged waist circumference was present in 56% with IFG
compared with 37.3% in normoglycemics, obesity prevalence was 38%
compared with 23.4%, and dyslipidemia 57.2% versus 44.8%.
"The metabolic state of pre-diabetes has a very significant burden of
cardiovascular risk," Dr. Williams told meeting attendees.
"If we could treat metabolic syndrome," a constellation of symptoms
including obesity, high waist-to-hip ratio, dyslipidemia, high blood
pressure and IFG, co-presenter Dr. David Eddy of Archimedes, Inc., said,
"we could reduce risk of cardiovascular disease by 63%."
Dr. Eddy, of Aspen, Colorado, is developing a mathematical model to
calculate the impact of modifiable cardiovascular risk factors, which
has been adopted by the ADA.
Kathrynne Holden, MS, RD < fivestar at nutritionucanlivewith.com >
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