[PHNUTR-L] Vitamin E levels,
cognitive impairment and dementia in older persons
Kathrynne Holden, MS, RD
fivestar at nutritionucanlivewith.com
Tue Mar 21 06:32:55 PST 2006
Colleagues, the following is FYI and does not necessarily reflect my own
opinion. I have no further knowledge of the topic. If you do not wish to
receive these posts, set your email filter to filter out any messages
coming from @nutritionucanlivewith.com and the program will remove
anything coming from me.
Low Plasma Vitamin E Levels Linked to Dementia and Cognitive Impairment
“Vitamin E levels, cognitive impairment and dementia in older persons:
the InCHIANTI study,” Cherubini A, Martin A, et al, Neurobiol Aging,
2005; 26(7): 987-94. (Address: Institute of Gerontology and Geriatrics,
University of Perugia Medical School, Department of Clinical and
Experimental Medicine, via Brunamonti, Policlinico Monteluce, Padiglione
E, Perugia 06122, Italy. E-mail: acherub at unipg.it ).
Summary: In a population-based cohort study involving 1,033 subjects
aged 65 years and older, low plasma levels of vitamin E were found to be
associated with a greater probability of becoming demented and of
suffering from cognitive impairment. Assessments were made of vitamin E
levels (via blood samples), diet, probability of being demented, and
probability of suffering from cognitive impairment (via clinical and
neuropsychological examinations) in all subjects. Results found that
after adjusting for age, gender, education, lipid levels, energy intake,
smoking, and vitamin E intake, subjects with the lowest plasma levels of
vitamin E (lowest tertile) had the greatest probability of becoming
demented, with an odds ratio of 2.6, and the greatest probability of
suffering from cognitive impairment, with an odds ratio of 2.2, as
compared to subjects with the highest plasma levels of vitamin E
(highest tertile). These results suggest that maintaining high plasma
levels of vitamin E may benefit the elderly by protecting against
cognitive impairment and dementia.
Kathrynne Holden, MS, RD < fivestar at nutritionucanlivewith.com >
"Ask the Parkinson Dietitian" http://www.parkinson.org/
"Eat well, stay well with Parkinson's disease"
"Parkinson's disease: Guidelines for Medical Nutrition Therapy"
More information about the PHNUTR-L