[PHNUTR-L] Eating a Fat-Rich Meal Positively Affects Postprandial
Early Insulin Secretion in Type 2 Diabetic Postmenopausal Women
fivestar at nutritionucanlivewith.com
Wed Dec 26 10:38:49 PST 2007
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Eating a Fat-Rich Meal Positively Affects Postprandial Early Insulin
Secretion in Type 2 Diabetic Postmenopausal Women
Reference: "Meal Composition affects insulin secretion in women with
type 2 diabetes: a comparison with healthy controls. The Hoorn prandial
study," Alssema M, Dekker JM, et al, Eur J Clin Nutr, 2007 Nov 7; [Epub
ahead of print]. (Address: EMGO Institute, VU University Medical Center,
Amsterdam, The Netherlands. E-mail: m.alssema at vumc.nl ).
Summary: In a study involving 76 normoglycemic and 64 type 2 diabetic
postmenopausal women, results indicate that consumption of a fat-rich
mixed meal may be associated with a higher insulinogenic index - a
measure of early insulin secretion following a meal - compared to
consumption of a carbohydrate-rich mixed meal, in type 2 diabetic women.
The participants received a fat-rich and carbohydrate-rich meal on
separate occasions. Normoglycemic women presented with higher
insulinogenic index than type 2 diabetic women. Insulinogenic index
following the fat-rich meal was higher than that after the
carbohydrate-rich meal (not significant in normoglycemic women). In type
2 diabetic women, homeostasis model assessment for insulin resistance
was positively associated with insulinogenic index following the
carbohydrate-rich meal. Additionally, in normoglycemic women, an
independent inverse association was observed between waist circumference
and insulinogenic index following the carbohydr ate-rich and fat-rich
meals. Thus, the authors of this study conclude, "The insulinogenic
index following the fat-rich meal was higher than following the
isocaloric carbohydrate-rich meal, which might favorably affect
postprandial glucose excursions, especially in women with type 2
diabetes. The association between a larger waist circumference and a
lower meal-induced insulinogenic index in normoglycemic women requires
further mechanistic studies."
Kathrynne Holden, MS, RD < fivestar at nutritionucanlivewith.com >
"Ask the Parkinson Dietitian" http://www.parkinson.org/
"Eat well, stay well with Parkinson's disease"
"Parkinson's disease: Guidelines for Medical Nutrition Therapy"
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