[PHNUTR-L] Intake of Carotenoids,
Antioxidants May Reduce the Risk of Early Age-Related Maculopathy
fivestar at nutritionucanlivewith.com
Mon Dec 31 18:24:11 PST 2007
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Intake of Carotenoids and other Antioxidants May Reduce the Risk of
Early Age-Related Maculopathy
Reference: "Intake of zinc and antioxidant micronutrients and early
age-related maculopathy lesions," Morris MS, Jacques PF, et al,
Ophthalmic Epidemiol, 2007; 14(5): 288-98. (Address: Jean Mayer U.S.
Department of Agriculture Human Nutrition Research Center on Aging at
Tufts University, Boston, Massachusetts 02111, USA. E-mail:
martha.morris at tufts.edu ).
Summary: In a study involving 398 women between the ages of 52 and 74
years, intake of various carotenoids and vitamins A and E was found to
be associated with a reduced prevalence of early age-related
maculopathy. The subjects' micronutrient intakes were assessed using
semi-quantitative food frequency questionnaires. Results found that the
prevalence of pigmentary abnormalities (PA) was significantly less among
subjects whose intakes of various carotenoids and antioxidants were
high. Specifically, energy-adjusted intakes of alpha-carotene,
beta-carotene, lycopene, total retinol, total vitamin A, and total
vitamin E were significantly inversely associated with the prevalence of
PA. Moreover, consumption of foods rich in alpha- or beta-carotene was
associated with a lower odds ratio of PA. Compared to women consuming
foods rich in alpha- or beta-carotene less than 5 times/week, those
consuming such carotenoid-rich foods 5-6 times/week had a 0.7 odds ratio
of PA, those consuming su ch foods 7-9.5 times/week had a 0.6 odds
ratio, and those consuming 10 or more servings/week of such foods had an
odds ratio of 0.3. No significant associations were found for zinc and
lutein/zeaxanthin. These results suggest that the prevalence of early
age-related maculopathy - for which macular degeneration, a leading
cause of blindness, is the end stage - may be reduced by intake of a
diet rich in alpha-carotene, beta-carotene, lycopene, retinol, vitamin
A, and vitamin E.
Kathrynne Holden, MS, RD < fivestar at nutritionucanlivewith.com >
"Ask the Parkinson Dietitian" http://www.parkinson.org/
"Eat well, stay well with Parkinson's disease"
"Parkinson's disease: Guidelines for Medical Nutrition Therapy"
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