[PHNUTR-L] High Blood Levels of Omega-3 Fatty Acids May Protect
Against Acute Coronary Syndrome
fivestar at nutritionucanlivewith.com
Tue Mar 6 17:50:14 PST 2007
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High Blood Levels of Omega-3 Fatty Acids May Protect Against Acute
Keywords: ACUTE CORONARY SYNDROME, HEART DISEASE - Omega-3 Fatty Acids,
DHA, EPA, Trans Fats
Reference: "Blood omega-3 and trans fatty acids in middle-aged acute
coronary syndrome patients," Harris WS, Reid KJ, et al, American Journal
of Cardiology, 2007; 99(2): 154-158. (Address: Sanford Research and
School of Medicine, University of South Dakota, Sioux Falls, South
Dakota, USA. E-mail: bill.harris at usd.edu ).
Summary: In a study involving 94 subjects with acute coronary syndrome
(ACS) and 94 controls, significantly lower blood levels of omega-3 fatty
acids (EPA and DHA) were found among subjects with ACS, as compared to
controls. 54% of subjects were male and 80% were Caucasian. Subjects
with ACS were found to have 29% lower whole blood long-chain omega-3
fatty acid content (EPA+DHA), as compared to controls (1.7 vs. 2.4).
Multivariable models adjusted for variables such as smoking status,
alcohol use, diabetes, BMI, serum lipids, and history of myocardial
infarction, found the odds for case status to be 0.67 for 1 standard
deviation increase in blood EPA plus DHA. Levels of trans fatty acids in
the blood did not significantly differ between the groups. The results
of this study suggest that low blood levels of the omega-3 fatty acids,
EPA and DHA, may increase the risk of ACS. The authors conclude, "Blood
EPA + DHA may serve as a new, modifiable risk factor for ACS."
Kathrynne Holden, MS, RD < fivestar at nutritionucanlivewith.com >
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