[PHNUTR-L] How Much Vitamin D3 do the Elderly Need?
fivestar at nutritionucanlivewith.com
Tue Mar 20 17:33:05 PDT 2007
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How Much Vitamin D3 do the Elderly Need?
Reference: "How much vitamin D3 do the elderly need?" Viljakainen HT,
Lamberg-Allardt C, et al, Journal of the American College of Nutrition,
2006; 25(5): 429-435. (Address: Department of Applied Chemistry and
Microbiology, University of Helsinki, Finland. E-mail:
christel.lamberg-allardt at helsinki.fi ).
Summary: In a study involving 49 elderly female subjects (aged 65-85
years), a clear dose-response relationship was found between vitamin D3
supplementation and levels of serum 25 hydroxy vitamin D (25(OH)D). The
subjects were randomly divided into four groups and received one of four
treatments for a period of 12 weeks. Group 1 received a placebo; Group 2
received 5 mu g/d vitamin D3; Group 3 received 10 mu g/d vitamin D3; and
Group 4 received 20 mu g/d vitamin D3. Levels of serum 25(OH)D were
assessed at the start of the study and every other week thereafter.
Results found significant increases in serum 25(OH)D levels among all
subjects who received supplementation with vitamin D3 (increases were
10.9 nmol/L among subjects who received 5 mu g/d; 14.4 nmol/L among
subjects who received 10 mu g/d; and 23.7 nmol/L among subjects who
received 20 mu g/d), while a decrease was found among subjects who
received the placebo. Subjects whose vitamin D status was lower at
baseline responded more efficiently to supplementation with vitamin D3,
as compared to subjects with higher vitamin D status at baseline. In
subjects with the highest dose-response to supplementation, levels of
serum intact parathyroid hormone tended to decrease. The authors
conclude, "The recommended dietary intake of 15 mu g/d is adequate to
maintain S-25-OHD concentration around 40-55 nmol/L during winter, but
if the optimal S-25-OHD is higher than that, even higher vitamin D
intakes are needed."
Kathrynne Holden, MS, RD < fivestar at nutritionucanlivewith.com >
"Ask the Parkinson Dietitian" http://www.parkinson.org/
"Eat well, stay well with Parkinson's disease"
"Parkinson's disease: Guidelines for Medical Nutrition Therapy"
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