[PHNUTR-L] Study suggests link between obesity, poor bone health
Kathrynne Holden
fivestar at nutritionucanlivewith.com
Tue Nov 27 08:46:59 PST 2007
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Public release date: 26-Nov-2007
http://www.eurekalert.org/pub_releases/2007-11/uog-ssl112607.php
Contact: Sam Fahmy
sfahmy at uga.edu
706-542-5361
University of Georgia
Study suggests link between obesity, poor bone health
Athens, Ga. – Being overweight is a known risk factor for heart disease,
diabetes and a host of other health conditions. Now, a University of
Georgia study published in the November issue of the American Journal of
Clinical Nutrition finds that obesity may also be bad for bone health.
Researchers conducted advanced three-dimensional bone scans on 115 women
ages 18 and 19 with normal (less than 32 percent) and high (greater than
32 percent) body fat. After adjusting for differences in muscle mass
surrounding the bone, the researchers found that the bones of
participants with high body fat were 8 to 9 percent weaker than those of
normal body fat participants.
“Obesity is an epidemic in this country, and I think this study is
critical because it highlights another potential negative health effect
that people haven’t considered,” said study co-author Richard D. Lewis,
professor of foods and nutrition at the UGA College of Family and
Consumer Sciences.
Previous studies on bone health and obesity used a two-dimensional bone
densitometer that is commonly used in osteoporosis screenings. Lewis
explained that a notable shortcoming of the bone densitometer is that it
does not take into account bone shape and geometry, which have a
substantial influence on bone strength. The new study used a
three-dimensional imaging technique that measures both the amount of
mineral in the bone and its shape and geometry. The study found that,
surprisingly, normal- and high body-fat young adult females have
comparable bone strength in a direct comparison that does not account
for muscle mass.
“The fact that the two groups had similar bone strength measures is
remarkable in itself, because you would expect it to be higher in the
heavier person,” Lewis said.
Doctoral candidate Norman Pollock, lead author of the study, explained
that muscle exerts force on bones, which stimulates bone growth.
Overweight people tend to have more muscle surrounding their bones than
their leaner counterparts, leading most researchers to assume that being
overweight is good for bone health.
“When we corrected for the amount of muscle, we found that the obese
person is not making as much bone as they should be for the amount of
muscle that they have,” Pollock said. “People haven’t observed that in
the past because they weren’t using the three-dimensional scan.”
Lewis said the exact mechanisms by which excess fat hinders bone
strength are unclear, but studies of obese rats show that they produce
more fat cells in the bone marrow and fewer bone cells. Since fat and
bone cells originate from the same precursor, it may be that fat cell
production is favored over bone cell production in obese people.
The women the researchers studied were 18 and 19, an age at which the
bones have stopped growing but before age-related degeneration begins.
Lewis said future studies using three-dimensional bone imaging should
follow children with normal and high levels of body fat through time to
see how their skeletons grow. Other researchers have documented
increased fractures in overweight children, suggesting that childhood
obesity may be particularly detrimental to bone health.
“When you’re young you have the capacity to change the shape of your
bones, but when you get older you don’t have that capacity.” Lewis said.
“And because of that, childhood obesity could have a significant, long
lasting negative impact on the skeleton.”
--
Kathrynne Holden, MS, RD < fivestar at nutritionucanlivewith.com >
"Ask the Parkinson Dietitian" http://www.parkinson.org/
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