[PHNUTR-L] Vitamin D Depletion Very Common in Patients Seeking
fivestar at nutritionucanlivewith.com
Thu Feb 21 08:21:39 PST 2008
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Vitamin D Depletion Very Common in Patients Seeking Osteoporosis Advice
Reference: "Prevalence of vitamin D depletion among subjects seeking
advice on osteoporosis: a five-year cross-sectional study with public
health implications," Guardia G, Parikh N, et al, Osteoporos Int, 2008;
19(1): 13-9. (Address: Sudhaker Rao, Bone & Mineral Research Laboratory,
Henry Ford Hospital, Detroit, MI, USA. E-mail: srao1 at hfhs.org ).
Summary: In a cross-sectional study involving 2,924 patients (mean age:
68.3 years; 90% women; 88% white) seeking osteoporosis advice, vitamin D
depletion - assessed by measuring levels of 25-hydroxyvitamin D - was
found to be highly prevalent. The mean 25(OH)D in subjects was 24.6
ng/ml, and the mean PTH was 48.4 pg/ml. Vitamin D depletion was found in
72% of subjects, when the cutoff was defined as having 25(OH)D level
less than 30 ng/mL. When the cutoff was defined as less than 20 ng/ml,
the prevalence decreased to 32%, and when the cutoff was defined as less
than 15 ng/ml, the prevalence further decreased to 15%. Cut-off levels
were stratified by gender, race, and the year of the study over 5 years.
Regardless of the cut-off level, men and blacks were found to have a
higher prevalence of vitamin D depletion. An inverse relationship was
found between 25(OH)D and PTH in all groups of subjects. The authors
conclude, "The prevalence of vitamin D depletion in patients seeking ad
vice for osteoporosis is high and did not change over the 5 years of the
Kathrynne Holden, MS, RD
"Ask the Parkinson Dietitian" http://www.parkinson.org/
"Eat well, stay well with Parkinson's disease"
"Parkinson's disease: Guidelines for Medical Nutrition Therapy"
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