[PHNUTR-L] Myo-inositol Found to be Safe and Effective Fertility
Treatment for Women with PCOS
fivestar at nutritionucanlivewith.com
Thu Feb 21 15:26:56 PST 2008
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Myo-inositol Found to be Safe and Effective Fertility Treatment for
Women with PCOS
Reference: "Myo-inositol in patients with polycystic ovarian syndrome:
A novel method for ovulation induction," Papaleo E, Unfer V, et al,
Gynecol Endocrinol, 2007; 23(12): 700-3. (Address: IVF Unit,
Gynaecological-Obstetric Department, IRCCS San Raffaele Hospital,
Vita-Salute University, Milan, Italy).
Summary: In a study involving 25 women of childbearing age with
polycystic ovarian syndrome (PCOS) exhibiting oligo- or amenorrhea and
infertility, supplementation with myo-inositol (an isoform of inositol
belonging to the vitamin B complex) combined with folic acid was found
to safely restore spontaneous ovarian activity and promote fertility.
Women received supplementation with Inofolic® - myo-inositol combined
with folic acid - 2 g, twice daily. During the treatment period, 22 of
the 25 women (88%) experienced a restoration of at least one spontaneous
menstrual cycle, out of which 18 (72%) maintained normal ovulatory
activity during the follow-up period. Ten of the patients (40%) became
pregnant (singletons); 9 clinical pregnancies were assessed with fetal
heart beat at ultrasound scan; and 2 pregnancies evolved in spontaneous
abortion. The authors conclude, "Myo-inositol is a simple and safe
treatment that is capable of restoring spontaneous ovarian activity and
consequent ly fertility in most patients with PCOS. This therapy did not
cause multiple pregnancy."
Kathrynne Holden, MS, RD
"Ask the Parkinson Dietitian" http://www.parkinson.org/
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"Parkinson's disease: Guidelines for Medical Nutrition Therapy"
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