[PHNUTR-L] Myo-inositol Found to be Safe and Effective Fertility Treatment for Women with PCOS

[Kathrynne Holden]

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	Myo-inositol Found to be Safe and Effective Fertility Treatment for 
Women with PCOS
http://www.vitasearch.com/CP/weeklyupdates/

Reference: 	"Myo-inositol in patients with polycystic ovarian syndrome: 
A novel method for ovulation induction," Papaleo E, Unfer V, et al, 
Gynecol Endocrinol, 2007; 23(12): 700-3. (Address: IVF Unit, 
Gynaecological-Obstetric Department, IRCCS San Raffaele Hospital, 
Vita-Salute University, Milan, Italy).

Summary: 	In a study involving 25 women of childbearing age with 
polycystic ovarian syndrome (PCOS) exhibiting oligo- or amenorrhea and 
infertility, supplementation with myo-inositol (an isoform of inositol 
belonging to the vitamin B complex) combined with folic acid was found 
to safely restore spontaneous ovarian activity and promote fertility. 
Women received supplementation with Inofolic® - myo-inositol combined 
with folic acid - 2 g, twice daily. During the treatment period, 22 of 
the 25 women (88%) experienced a restoration of at least one spontaneous 
menstrual cycle, out of which 18 (72%) maintained normal ovulatory 
activity during the follow-up period. Ten of the patients (40%) became 
pregnant (singletons); 9 clinical pregnancies were assessed with fetal 
heart beat at ultrasound scan; and 2 pregnancies evolved in spontaneous 
abortion. The authors conclude, "Myo-inositol is a simple and safe 
treatment that is capable of restoring spontaneous ovarian activity and 
consequent ly fertility in most patients with PCOS. This therapy did not 
cause multiple pregnancy."
-- 
Kathrynne Holden, MS, RD
"Ask the Parkinson Dietitian"  http://www.parkinson.org/
"Eat well, stay well with Parkinson's disease"
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