[PHNUTR-L] Supplementation with Probiotics May Enhance Eradication
of H. Pylori
fivestar at nutritionucanlivewith.com
Fri Feb 29 06:39:47 PST 2008
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Supplementation with Probiotics May Enhance Eradication of H. Pylori
Reference: "The effect of probiotics on Helicobacter pylori
eradication," Park SK, Park DI, et al, Hepatogastroenterology, 2007;
54(79): 2032-6. (Address: Department of Internal Medicine, Kangbuk
Samsung Hospital, Sungkyunkwan University School of Medicine, Jongno-gu,
Seoul 110-746, Korea).
Summary: In a study involving 352 patients infected with Helicobacter
pylori, supplementation with probiotics was found to improve drug
compliance, reduce side effects, and enhance the intention-to-treat
eradication rate of H. pylori. Subjects were randomized into 2 groups.
One group received probiotics (bacillus subtilis and Streptococcus
faecium) plus standard triple therapy (2 antibiotics plus a proton pump
inhibitor), while the other group received standard triple therapy
alone. Probiotics were given for 8 weeks. Four weeks after completion of
therapy, results of intention to treat analysis found that subjects in
the probiotics group experienced higher eradication of H. pylori
(83.5%), compared to subjects in the triple therapy alone group (73.3%).
Side effects of triple therapy, including diarrhea, were more common in
the triple therapy alone group. Results of this study suggest that
adding probiotic supplementation to standard pharmacological therapy
used to treat H. pylor i infection ('triple therapy') may enhance
eradication of H. pylori and reduce side effects, thereby rendering
treatment more tolerable and effective.
Kathrynne Holden, MS, RD
"Ask the Parkinson Dietitian" http://www.parkinson.org/
"Eat well, stay well with Parkinson's disease"
"Parkinson's disease: Guidelines for Medical Nutrition Therapy"
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