[PHNUTR-L] Dietary Fiber Intake May Help Reduce the Risk of Endometrial Cancer

[Kathrynne Holden]

Colleagues, the following is FYI and does not necessarily reflect my own
opinion. I have no further knowledge of the topic. If you do not wish to
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Dietary Fiber Intake May Help Reduce the Risk of Endometrial Cancer
http://www.vitasearch.com/CP/weeklyupdates/

Reference: 	"Association between dietary fiber and endometrial cancer: a 
dose-response meta-analysis," Bandera EV, Kushi LH, et al, American 
Journal of Clinical Nutrition, 2007; 86(6): 1730-1737. (Address: The 
Cancer Institute of New Jersey, Robert Wood Johnson Medical School, New 
Brunswick, NJ 08903, USA. E-mail: elisa.bandera at umdnj.edu).

Summary: 	In a dose-response meta-analysis of studies examining the 
relationship between dietary fiber consumption and endometrial cancer 
risk, an inverse association was found between dietary fiber intake and 
endometrial cancer. The authors conducted a systematic literature review 
of articles published through February 2007 and identified 10 studies 
for analysis (1 case-cohort study and 9 case-control studies). The 
random-effects summary risk estimate was found to be 0.82 per 5 g/1000 
kcal dietary fiber (based on 7 case-control studies), with no evidence 
of heterogeneity. Comparing the highest versus the lowest intakes of 
dietary fiber, the random-effects summary estimate was 0.71, with no 
evidence of heterogeneity either (ased on 8 case-control studies). In 
the one prospective study which evaluated the association between 
dietary fiber intake and endometrial cancer, results did not show a 
beneficial effect of fiber consumption. The authors conclude, "Although 
the current evidenc e, based on data from case-control studies, supports 
an inverse association between dietary fiber and endometrial cancer, 
additional population-based studies, particularly cohort studies, are 
needed before definitive conclusions can be drawn."
-- 
Kathrynne Holden, MS, RD < fivestar at nutritionucanlivewith.com >
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